_{15th May, 2026}

Principal Analytical Chemist 
SE England 
Permanent
 
Our SE based client is currently looking to recruit a Principal Analytical Chemist to perform complex method development and validation using LC-MS / HPLC on a variety of synthesised chemicals and API molecules.
This is a hands-on role and would suit someone who enjoys developing novel methods from first principles in busy commercial manufacturing environment.
 
Additional duties for this role will include :

• Leading a small team of Analytical Chemists, assisting with ongoing project work when required
• Instrument and method trouble-shooting , solving problems to enable analyses to be completed
• Working with Synthetic / Process Chemists to understand synthesised chemicals to ultimately ensure the successful analysis of a range of molecules
• Leading on a number of analytical projects, understanding GMP requirements and defining scope of analytical projects and milestones
• Understanding / performing analyses with a range of other chromatography, spectroscopy and techniques (including NMR, ICP and others)
• Completing detailed GMP documentation and reports, ensuring analytical success 
• Understanding new approaches in analytical methodologies and techniques and implementing method improvements
• Training and mentoring others, leading by example on complex problem solving challenges

Applications are invited from candidates with a BSc, MSc, PhD in Analytical Chemistry (or similar) together with proven demonstrable hands-on skills performing complex GMP method development and validation using chromatography systems in an API / synthesis environment
 
For further information or to apply please contact martin@entrustrs.com 01606 818294
 
This is a permanent role offering an attractive salary depending on skills and experience
Role : Permanent
Location : SE England

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