_{20th May, 2026}

Who are we?
We’re Avance Clinical a Contract Research Organisation. We offer specialised services supporting drug development for the pharmaceutical and biotechnology industry. We have a rich history in this area with our founding roots dating back to the 1980’s. If you already work in this industry you’ll know that we are experts in our field.

Why should you join Avance Clinical?
We appreciate that our most important asset is our people. We offer a fun, friendly work environment and a culture that values honesty and respect. We have a strong sense of team. We genuinely appreciate each individual but recognise the collective when achieving success.

We are committed to creating a flexible work environment for our people by supporting them to balance their work commitments and personal needs, both now and into the future.

Broad Purpose
Avance Clinical is a Contract Research Organization which offers specialized services supporting drug
development for the pharmaceutical and biotechnology industry.

The Senior Manager, Investigator Contracts and Payments, North America (NA) provides customer-focused
leadership in the delivery of site budget and contract negotiation, and site payment services, in accordance with
the study budget, protocol, Standard Operating Procedures (SOPs), ICH GCP guidelines and other applicable
regulatory requirements.

The Senior Manager, Investigator Contracts and Payments NA is also responsible for line management of the
Investigator Contracts and Payments Team including resource management, service provision, departmental
systems/procedures development, implementation and support, team performance and compliance, and risk
identification/mitigation.
 
Core Responsibilities

• During the Study Start-Up (SSU) phase, develop, manage or oversee site budget negotiation and
  contracting timelines and regularly report progress including plans to address potential timing
  risks/gaps. If planned timelines are not reached, analyze data to provide clear rationale for delays,
  provide contingency plans to mitigate impact, and escalate the issue as soon as identified.
• Serve as the primary contact with the Sponsor, PM, other Functional Leads and Third Parties who have
  involvement in site budget negotiation, site contracting, and investigator payments. Report on
  status/metrics at sponsor meetings and communicate outcomes to project team.
• Review Non-Disclosure / Confidentiality Agreements for sites, vendors and sponsors.
• Develop and/or review study-specific country-level site budgets for accuracy and compliance with Sponsor and Avance requirements.
• Develop and/or review study-specific site budgets for accuracy and compliance with Sponsor and
  Avance requirements. Review proposed site budget items for Fair Market Value (FMV) analysis to
  determine audit risk.
• Develop and/or review study-specific country-level site Clinical Trial Agreement ensuring accuracy and
  compliance with Sponsor and Avance requirements.
• Review proposed Clinical Trial Agreement
  language for risk level and liaise with sponsor for review.
• Review final Clinical Trial Agreement (CTA) and budget for accuracy and ensure all required sponsor
  approvals are in place prior to execution.
• Develop and/or review study-specific country-level site budget estimates for use in proposals. Defend
  estimates at sponsor meetings (if required).
• Audit site invoices submitted to accounts payable for accuracy and compliance, and process the
  corresponding site payments in line with CTA requirements.
• Review and audit total costs paid to site at close-out to prepare final accounting reconciliation.
• Review annual report of site payments for sponsor Sunshine Act reporting, where applicable.
• Manage Investigator Contracts and Payments Team resource assignments across the department,
  proactively projecting resource need.
• Actively manage the performance of line reports and establish/manage individual career development
  strategies. Provide guidance and mentoring to less experienced Investigator Contracts and Payments
  Team members and implement training initiatives.
• Implement and support staff retention initiatives, drive staff recruitment (including interviews and
  probation period management), and manage staff severance.
• Monitor line reports' compliance with training and timecard entry, conduct weekly timecard review
  and tracking, leave entitlement administration; and review and approve line reports' expense reports.
• Other duties as directed by Line Manager or delegate.

Departmental Responsibilities

• Foster the on-going commitment to maintaining a healthy team culture and promoting good morale, by
  actively participating in regular Project Delivery Team meetings.
• Maintain effective communication with other members of the department.
• Proactively identify risks related to departmental service provision and assist in their mitigation and resolution.
• Manage and track business related expenses as per company policy.
• Identify training needs of the Investigator Contracts and Payments Team; develop and deliver appropriate
  training programs.
• Lead the development of relevant departmental Standard Operating Procedures (SOPs) and processes.
• Develop and maintain Clinical Trial Agreement template.
• Collaborate across departments to enhance and optimize systems impacting multiple teams, such as Veeva.
• Participate in study-specific or vendor audits conducted by sponsors or regulatory agencies, and respond to
  audit observations, as required.

Qualifications, Skills and Experience

• Bachelor's level degree in accounting, law, life sciences, pharmacy, nursing or equivalent field (highly
  regarded), or appropriate industry experience.
• Previous experience in an equivalent role in a Contract Research Organization (CRO), Pharma company or
  investigator site, or previous experience with at least 10 years site contract experience in the relevant region.
• Previous training and a working knowledge of ICH GCP and applicable regulatory requirements.
• Clear understanding of the requirement to adhere strictly to client confidentiality.
• Effective written and oral communications skills, including the ability to keep clients, senior management and
  other stakeholders informed of project updates and other pertinent information.
• Demonstrated ability to take initiative in problem solving and in exercising good judgment.
• An understanding of Privacy Legislation as it applies to the Clinical Trial Environment.
• Ability to work under pressure in a multi-disciplinary team environment.
• Willingness to work in, and be supportive of, a positive and dynamic team culture.

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